Protein Info for QEN71_RS02455 in Paraburkholderia sabiae LMG 24235

Annotation: L-threonylcarbamoyladenylate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 347 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family" amino acids 14 to 216 (203 residues), 162.3 bits, see alignment E=4.2e-52 PF01300: Sua5_yciO_yrdC" amino acids 25 to 205 (181 residues), 179.1 bits, see alignment E=6e-57 PF03481: Sua5_C" amino acids 207 to 340 (134 residues), 81.1 bits, see alignment E=1.1e-26

Best Hits

KEGG orthology group: K07566, putative translation factor (inferred from 96% identity to bph:Bphy_0465)

Predicted SEED Role

"TsaC protein (YrdC-Sua5 domains) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (347 amino acids)

>QEN71_RS02455 L-threonylcarbamoyladenylate synthase (Paraburkholderia sabiae LMG 24235)
MPDQMKPADVTSSVSADEIAHAAALLDAGQLVAFPTETVYGLGGDAESPDAVARIYAAKG
RPANHPVIVHLAPNGDPNYWVAQLPSEAQRLIDAFWPGPLTLILKRAAHIPAAVSGGQDS
VGLRCPSHPVAQSLLAAFSALRNGHGGVAAPSANRFGHVSPTTAQHVRDEFGDAIHVLDG
GSSDVGIESTIVDLSRGFPALLRPGHVTPQDIADVLGEMPRLPDGSDASAPRASGTLKAH
YAPRTRLALLPFDVLEPLLAARAPGERVALVARASRAGHWAEASDVHFVAAPEDPHLYAR
DLYGLLRALDRANVSRILIEKLPDTIEWIAVNDRLGRAAAAFEANEA