Protein Info for QEN71_RS02020 in Paraburkholderia sabiae LMG 24235

Annotation: ubiquinone biosynthesis regulatory protein kinase UbiB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 527 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 501 to 524 (24 residues), see Phobius details TIGR01982: 2-polyprenylphenol 6-hydroxylase" amino acids 3 to 441 (439 residues), 552.3 bits, see alignment E=3.4e-170 PF03109: ABC1" amino acids 87 to 340 (254 residues), 247.8 bits, see alignment E=4.6e-78

Best Hits

Swiss-Prot: 99% identical to UBIB_PARP8: Probable protein kinase UbiB (ubiB) from Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)

KEGG orthology group: K03688, ubiquinone biosynthesis protein (inferred from 99% identity to bph:Bphy_0377)

Predicted SEED Role

"Ubiquinone biosynthesis monooxygenase UbiB" in subsystem Ubiquinone Biosynthesis

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (527 amino acids)

>QEN71_RS02020 ubiquinone biosynthesis regulatory protein kinase UbiB (Paraburkholderia sabiae LMG 24235)
MRFLRFLKIFFTVIRFGLDEMMLSRVNDRRVRLLLRITTIGRKFDQPPGVRLRLALESLG
PIFVKFGQVLSTRRDLLRPDIASELAKLQDQVPPFDSAVAIAIIEKSLGAPVDTIFDDFE
RVPVASASIAQVHFATLKTGQHAGKQVAVKVLRPNMLPVIDSDLALLRDIAVWAERLWAD
GKRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMYWEYCTANVLVM
ERMVGVPISQVDTLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPAHF
GRYIALDFGIIGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPATTRVEELESAI
RAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPEL
DLWKTAKPYLERWMNEQIGAKGWYERLKIEAPQWSKTLPQLPRLIHHALAQRHDAQQRGI
NDETIRQILLEQKRTNRLLQGLLMFGVAVGIGAVLARAWLAIAYGGY