Protein Info for QEN71_RS01785 in Paraburkholderia sabiae LMG 24235

Annotation: cation:proton antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 667 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 57 to 76 (20 residues), see Phobius details amino acids 85 to 107 (23 residues), see Phobius details amino acids 113 to 137 (25 residues), see Phobius details amino acids 150 to 173 (24 residues), see Phobius details amino acids 180 to 200 (21 residues), see Phobius details amino acids 220 to 236 (17 residues), see Phobius details amino acids 241 to 260 (20 residues), see Phobius details amino acids 272 to 291 (20 residues), see Phobius details amino acids 297 to 320 (24 residues), see Phobius details amino acids 328 to 349 (22 residues), see Phobius details amino acids 356 to 377 (22 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 9 to 377 (369 residues), 229 bits, see alignment E=1.3e-71 PF02254: TrkA_N" amino acids 413 to 526 (114 residues), 81.5 bits, see alignment E=9.3e-27 PF02080: TrkA_C" amino acids 588 to 656 (69 residues), 43.2 bits, see alignment E=4.5e-15

Best Hits

KEGG orthology group: K03455, monovalent cation:H+ antiporter-2, CPA2 family (inferred from 99% identity to bph:Bphy_0332)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system protein KefB" in subsystem Glutathione-regulated potassium-efflux system and associated functions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (667 amino acids)

>QEN71_RS01785 cation:proton antiporter (Paraburkholderia sabiae LMG 24235)
MISPLEMTLFLLLASVVGVVVFRYLNLPPMLGYLSVGIVVGPHAFGIVPDSVGAQNLAEF
GVVFLMFSIGLEFSLAKLRAMRRLVFGMGLLQVLGTIAVAVSLGFVFERWVHISWQASVA
LGGALAMSSTAIVSKMLAERLEIESEHGRNIFGVLLFQDLAVVPLLIVIAALGGSSDDLM
KSLGIASIKIVIALSLLLIVGQKFMTRWFNVVARRRSQELFILNLLLVTLGAAFITDKFG
LSLALGAFIAGMLIAETPYRHQVEEDIKPFRDVLLGLFFVTTGMLLNPRVIWEHPLIVLA
FLIGPVLLKAVMITGLARLFGATPGVAMRTGIGLAQAGEFGFVLLNLILDKHLVDATLLQ
AILAAMLLSMLAAPFMIQNADRIVLRLSSTEWMMQSLQMTRIATQSLKQSGHVIICGYGR
AGQNLARMLEHEGLSYVALDLDPDRVAAAAAAGESVVFGDAGRRESLLAAGIHRAATVAI
TYANTPSALRVLHNIHELEPTLPVIVRTVDDSDLEKLLAAGATEVIPEIVEGSLMLASHT
LVVMGVPMRRVVRRVEELRDERYSLLRGYFHGADDVEDDDGHEQVRLQSVPVDEKADAVG
RTLEELGLFDLGVEVTAIRRHGIRGVEPDPSTKLRASDIVVLRGLPEALAEAEERLSKHR
RAGAAAA