Protein Info for QEN71_RS01520 in Paraburkholderia sabiae LMG 24235

Annotation: cytochrome c oxidase subunit 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details amino acids 83 to 107 (25 residues), see Phobius details amino acids 154 to 168 (15 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 221 to 245 (25 residues), see Phobius details amino acids 265 to 284 (20 residues), see Phobius details PF00510: COX3" amino acids 10 to 284 (275 residues), 192.9 bits, see alignment E=4.7e-61

Best Hits

KEGG orthology group: K02276, cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 97% identity to bph:Bphy_0281)

MetaCyc: 51% identical to cytochrome c oxidase subunit 3 (Pseudomonas putida KT2440)

Predicted SEED Role

"Cytochrome c oxidase polypeptide III (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>QEN71_RS01520 cytochrome c oxidase subunit 3 (Paraburkholderia sabiae LMG 24235)
MSGQNESPYYFIPHPSRHPISAAIGLLVMLGSFAAWVNGEPWAPITALIGLLWLLFTLYH
WFGDAISESEGGMYGKRVDASYRWSMSWFIFSEVMFFGAFFGALFYARQIAMHQLGSLDY
KLIWPDFSAVWPNIGPADLVSHFKSMTPWPVPTINTALLLSSGATLTVSHHALRDNHRTK
AIAWLAATLVLGVSFLFLQGFEYFHAYNELNLTLASGVYGSTFFLLTGFHGFHVFLGGTM
LAIVMIRLIRGHFTADHHFAFEGAAWYWHFVDVVWLGLYVVVYWL