Protein Info for QEN71_RS01500 in Paraburkholderia sabiae LMG 24235

Annotation: cytochrome c oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 537 transmembrane" amino acids 41 to 62 (22 residues), see Phobius details amino acids 83 to 105 (23 residues), see Phobius details amino acids 125 to 151 (27 residues), see Phobius details amino acids 166 to 192 (27 residues), see Phobius details amino acids 204 to 232 (29 residues), see Phobius details amino acids 256 to 281 (26 residues), see Phobius details amino acids 289 to 311 (23 residues), see Phobius details amino acids 324 to 345 (22 residues), see Phobius details amino acids 358 to 381 (24 residues), see Phobius details amino acids 392 to 415 (24 residues), see Phobius details amino acids 434 to 454 (21 residues), see Phobius details amino acids 473 to 495 (23 residues), see Phobius details TIGR02891: cytochrome c oxidase, subunit I" amino acids 30 to 536 (507 residues), 700.5 bits, see alignment E=6.2e-215 PF00115: COX1" amino acids 38 to 479 (442 residues), 538 bits, see alignment E=8.8e-166

Best Hits

Swiss-Prot: 57% identical to COX1_BRADU: Cytochrome c oxidase subunit 1 (ctaD) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K02274, cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 98% identity to bph:Bphy_0277)

MetaCyc: 71% identical to cytochrome c oxidase subunit 1 (Pseudomonas putida KT2440)

Predicted SEED Role

"Cytochrome c oxidase polypeptide I (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (537 amino acids)

>QEN71_RS01500 cytochrome c oxidase subunit I (Paraburkholderia sabiae LMG 24235)
MSSIGHDVAAGHEHVHGDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALG
IRAELFEPGLQIMRPEFFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARM
NNFSFWLLPVAAVLLVGSFFTPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIM
GGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSF
FNAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASI
AILSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWVATMWRGSLTFETPMLF
AVGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFGLFSGWYYWSPKW
TGWMYNETRGKIHFWASLIFFNLAFLPMHFVGLAGMPRRYADYPAQFTDWNQVITIGAFG
FGLAQVYFLFAVALPAYRGGGELEQAGDKPWDGATGLEWTVPSPAPFHTFENPPTVE