Protein Info for QEN71_RS01330 in Paraburkholderia sabiae LMG 24235

Annotation: Na/Pi cotransporter family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 47 to 70 (24 residues), see Phobius details amino acids 76 to 100 (25 residues), see Phobius details amino acids 104 to 121 (18 residues), see Phobius details amino acids 132 to 153 (22 residues), see Phobius details amino acids 175 to 197 (23 residues), see Phobius details amino acids 206 to 229 (24 residues), see Phobius details amino acids 238 to 262 (25 residues), see Phobius details TIGR00704: Na/Pi-cotransporter II-related protein" amino acids 1 to 300 (300 residues), 302.3 bits, see alignment E=5.3e-94 PF02690: Na_Pi_cotrans" amino acids 13 to 147 (135 residues), 121.7 bits, see alignment E=2.4e-39 TIGR01013: sodium-dependent inorganic phosphate (Pi) transporter" amino acids 85 to 521 (437 residues), 321.2 bits, see alignment E=1.2e-99 PF01895: PhoU" amino acids 340 to 425 (86 residues), 54.2 bits, see alignment E=1.6e-18

Best Hits

Swiss-Prot: 58% identical to YJBB_ECO57: Uncharacterized protein YjbB (yjbB) from Escherichia coli O157:H7

KEGG orthology group: K03324, phosphate:Na+ symporter (inferred from 96% identity to bph:Bphy_0218)

MetaCyc: 57% identical to putative inorganic phosphate export protein YjbB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-470

Predicted SEED Role

"Sodium-dependent phosphate transporter" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (560 amino acids)

>QEN71_RS01330 Na/Pi cotransporter family protein (Paraburkholderia sabiae LMG 24235)
MLILLNLLSGVALLVWGTHIVRTGILRVWGADLRRALARSTNSRVKAFAAGVGVTSLVQS
SNATAMIVTSFAAQGMLPLACGLAIMLGADVGTALMARILTLDLSWLSPFLIVFGVPLFL
SRKQNRLGQVGRTAIGLGLILLALHLIVESAQPMMHGAGVRVMFGALTGDTMLDALVGAT
FAVISYSSLAAVLLTATLASSGVISLKVALCLVIGANLGSGLLALAGTLAQNTAARRLAL
GSLAFKLAGALLILPFTSLLARGLPVLINNPREAVVGFHVIYNTLRCCACLPLIDAVARA
SCRVLPERPEPNGQLHPIHLDTASIATPTLALANAAREVLRIGDIVRAMLDNVSHLIHHN
DPNKARDTIRMDDDVDHLYAEVKAYLARVSREQLDDADSRRWTDIIALTINLEHAGDIIE
RIVTDIEEKKIAHRLAFSEEGLAELDDLHTRLVGNLQLGMSVFLNNDLRCAELLLAEKER
FRDLERAYSYKHLDRLAGETLRSIETSALHLDVISDMKRLNSLFCSTAYPVLDAAGALHD
TRLRKRMHDAVPAVTLTQPP