Protein Info for Psyr_3663 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Protein of unknown function DUF6

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 signal peptide" amino acids 7 to 8 (2 residues), see Phobius details amino acids 26 to 27 (2 residues), see Phobius details transmembrane" amino acids 9 to 25 (17 residues), see Phobius details amino acids 42 to 63 (22 residues), see Phobius details amino acids 75 to 94 (20 residues), see Phobius details amino acids 105 to 122 (18 residues), see Phobius details amino acids 129 to 147 (19 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details amino acids 220 to 240 (21 residues), see Phobius details amino acids 250 to 272 (23 residues), see Phobius details amino acids 284 to 308 (25 residues), see Phobius details PF00892: EamA" amino acids 10 to 143 (134 residues), 67 bits, see alignment E=9.9e-23 amino acids 161 to 299 (139 residues), 49.6 bits, see alignment E=2.4e-17

Best Hits

Swiss-Prot: 42% identical to YHBE_ECOLI: Uncharacterized inner membrane transporter YhbE (yhbE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_3663)

Predicted SEED Role

"membrane protein, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZQ77 at UniProt or InterPro

Protein Sequence (319 amino acids)

>Psyr_3663 Protein of unknown function DUF6 (Pseudomonas syringae pv. syringae B728a ΔmexB)
MHISSGRWVYGLCLSLLTALLWGILPIKLKQVLQVMDPVTVTWFRLAVSGALLFIWLASV
GRLPSFKMLGRKGRVLVGLAVFGLVGNYVLYLIGLRLLSPGTTQLLVQVGPIFLLISSIF
LFKERFSLGQGIGLMVLLVGFGFFFNQRLVELFTSLGDYTLGVLVVLLASTIWTFYGLSQ
KQLLTVWNSLQVMMVIYLFCALLLTPWAHPAEALLLSPLQGWLLLACCLNTLVAYGAFAE
ALAHWEASRVSATLALTPLVTLTAVALAAWLWPDYVQAEELNVMGYGGALLVVAGSALTA
LGPSLVAGLRARKARLAQA