Protein Info for Psyr_3614 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Protein of unknown function DUF25

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00357: methionine-R-sulfoxide reductase
  • amino acids 6 to 130 (125 residues), 195.4 bits, E=1.8e-62
• PF01641: SelR
  • amino acids 10 to 128 (119 residues), 187.5 bits, E=3.5e-60

Best Hits

Swiss-Prot: 100% identical to MSRB_PSEU2: Peptide methionine sulfoxide reductase MsrB (msrB) from Pseudomonas syringae pv. syringae (strain B728a)

KEGG orthology group: K07305, peptide-methionine (R)-S-oxide reductase [EC: 1.8.4.12] (inferred from 100% identity to psb:Psyr_3614)

MetaCyc: 57% identical to methionine sulfoxide reductase B (Escherichia coli K-12 substr. MG1655)
L-methionine (R)-S-oxide reductase. [EC: 1.8.4.14]; Peptide-methionine (R)-S-oxide reductase. [EC: 1.8.4.14, 1.8.4.12]

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)" (EC 1.8.4.12)

KEGG Metabolic Maps

• Methionine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.4.12 or 1.8.4.14

Sequence Analysis Tools

See Q4ZQC6 at UniProt or InterPro

Protein Sequence (131 amino acids)

>Psyr_3614 Protein of unknown function DUF25 (Pseudomonas syringae pv. syringae B728a ΔmexB)
MDKLQKTLEEWKQMLDPEQYNVCRLKGTERPFSGKYDKVKTDGIYHCICCDEPLFDSTTK
FDSGCGWPSFYAPLENSAVIEVRDMSHGMIRTEVVCAKCDAHLGHVFPDGPPPTGLRYCI
NSVCLDLVPRS