Protein Info for Psyr_3353 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Catalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00199: Catalase
  • amino acids 31 to 408 (378 residues), 547.3 bits, E=2.1e-168
• PF06628: Catalase-rel
  • amino acids 432 to 492 (61 residues), 61.9 bits, E=5.2e-21

Best Hits

Swiss-Prot: 98% identical to CATB_PSESY: Catalase (katB) from Pseudomonas syringae pv. syringae

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 100% identity to psb:Psyr_3353)

MetaCyc: 45% identical to catalase monomer (Homo sapiens)
Catalase. [EC: 1.11.1.21, 1.11.1.6]; 1.11.1.6 [EC: 1.11.1.21, 1.11.1.6]

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethanol degradation IV (3/3 steps found)
• superoxide radicals degradation (2/2 steps found)
• methanol oxidation to formaldehyde IV (1/2 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.21 or 1.11.1.6

Sequence Analysis Tools

See Q4ZR37 at UniProt or InterPro

Protein Sequence (510 amino acids)

>Psyr_3353 Catalase (Pseudomonas syringae pv. syringae B728a ΔmexB)
MPLLNWSRHMVCLTAAGLITVPTVYAADTLTRDNGAVVGDNQNSQTAGAQGPVLLQDVQL
LQKLQRFDRERIPERVVHARGTGVKGEFTASADISDLSKATVFKSGEKTPVFVRFSSVVH
GNHSPETLRDPHGFATKFYTADGNWDLVGNNFPTFFIRDAIKFPDMVHAFKPDPRTNLDN
DSRRFDFFSHVPEATRTLTLLYSNEGTPAGYRFMDGNGVHAYKLVNAKGEVHYVKFHWKS
LQGLKNLDPKEVAQVQSKDYSHLTNDLVGAIKKGDFPKWDLYVQVLKPEELAKFDFDPLD
ATKIWPDVPEKKIGQMVLNKNVDNFFQETEQVAMAPANLVPGIEPSEDRLLQGRVFSYAD
TQMYRLGANGLSLPVNQPKVAVNNGNQDGALNTGHTTSGVNYEPSRLEPRPADDKARYSQ
LPLSGTTQQAKITREQNFKQAGDLYRSYSAKEKTDLVQSFGESLADTDTESKNIMLSYLY
KADPDYGTRVAEVAKGDLSKVKSLAASLKD