Protein Info for Psyr_2895 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01066: CDP-OH_P_transf
  • amino acids 1 to 166 (166 residues), 135.4 bits, E=1.1e-43
• TIGR00560: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
  • amino acids 1 to 179 (179 residues), 187.2 bits, E=2.1e-59

Best Hits

Swiss-Prot: 61% identical to PGSA_SHIF8: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA) from Shigella flexneri serotype 5b (strain 8401)

KEGG orthology group: K00995, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [EC: 2.7.8.5] (inferred from 97% identity to pst:PSPTO_3022)

MetaCyc: 61% identical to CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Escherichia coli K-12 substr. MG1655)
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [EC: 2.7.8.5]

Predicted SEED Role

"CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.8.5)

MetaCyc Pathways

• phosphatidylglycerol biosynthesis I (5/6 steps found)
• phosphatidylglycerol biosynthesis II (5/6 steps found)
• superpathway of phospholipid biosynthesis III (E. coli) (9/12 steps found)
• cardiolipin biosynthesis II (2/3 steps found)
• cardiolipin biosynthesis I (1/3 steps found)
• cardiolipin biosynthesis III (1/3 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (8/13 steps found)
• type I lipoteichoic acid biosynthesis (S. aureus) (4/17 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.5

Sequence Analysis Tools

See Q4ZSE3 at UniProt or InterPro

Protein Sequence (186 amino acids)

>Psyr_2895 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Pseudomonas syringae pv. syringae B728a ΔmexB)
MNIPNLITVLRVLLIPIFILLFYMPYHWSYMAASAVFAFAAATDWLDGYLARRLEQSTPF
GAFLDPVADKLMVAVALVLLVQAHANLWLTLPAAVIIGREIVISALREWMAEIGARAQVA
VSNMGKWKTAAQMLALVILLGNPPAITLWVILGYALLLIAAGLTLWSMVQYLRAAWPHLR
TTSEKK