Protein Info for Psyr_2878 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 542 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 5 to 178 (174 residues), 54.9 bits, see alignment E=8.5e-19 PF00015: MCPsignal" amino acids 326 to 507 (182 residues), 130.7 bits, see alignment E=5.4e-42

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_2878)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZSG0 at UniProt or InterPro

Protein Sequence (542 amino acids)

>Psyr_2878 Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer (Pseudomonas syringae pv. syringae B728a ΔmexB)
MLRQLKIAARTSACFALMVVLVFGLGIFSIQQLHGIREQSLEIENDALPGIALGDDIALA
VEKTRTTVAKMLAAHDMAQVTLAHTEFLDRKAGFQKAVEAYDPLITEDDERALVEGLKST
YQGYIERAEKVYTLINENQAEAGRALVWGEMKVMAEGMETALGKLEKINDDSEAESSAAA
TSVYENALIVTQGVMFLTVLLTVLLAWRLTKSLAVPISQALHSSETIAAGDLRPSAINRE
GTDEAALLLQSMERMRGNLSQTLSQVGDAAHQLASATEEMSALMVNSNADLVVQNSEIEM
AATAVTEMSQAVDEVARNAVTTSVESRASSVSAREGQEELNQTVKSILELTRNVGTASVE
AQALATRTLDITKVLDVIRAVSEQTNLLALNAAIEAARAGDAGRGFAVVADEVRALAHRT
SESTREIETMVGHIQQGTKSTLLALEVSTEQAQRTKQQAESANAVLASIASSVMVIDERN
TVIASASEEQALVAREVDRNLVRIRDLSAQSAVRTSQTGSASQSLAELASDLTITLGQFK
LG