Protein Info for PfGW456L13_526 in Pseudomonas fluorescens GW456-L13

Annotation: Inner membrane component of tripartite multidrug resistance system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 27 to 46 (20 residues), see Phobius details amino acids 67 to 85 (19 residues), see Phobius details amino acids 94 to 114 (21 residues), see Phobius details amino acids 120 to 145 (26 residues), see Phobius details amino acids 152 to 171 (20 residues), see Phobius details amino acids 184 to 204 (21 residues), see Phobius details amino acids 216 to 237 (22 residues), see Phobius details amino acids 244 to 265 (22 residues), see Phobius details amino acids 286 to 309 (24 residues), see Phobius details amino acids 323 to 345 (23 residues), see Phobius details amino acids 352 to 376 (25 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details amino acids 423 to 439 (17 residues), see Phobius details amino acids 479 to 500 (22 residues), see Phobius details PF07690: MFS_1" amino acids 34 to 342 (309 residues), 80.6 bits, see alignment E=5.3e-27

Best Hits

KEGG orthology group: None (inferred from 89% identity to pfo:Pfl01_0142)

Predicted SEED Role

"Inner membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QJV3 at UniProt or InterPro

Protein Sequence (510 amino acids)

>PfGW456L13_526 Inner membrane component of tripartite multidrug resistance system (Pseudomonas fluorescens GW456-L13)
MTSLTVTAPVAAASTAAAPPVFGPRIIIGLVGVLVAVLISGLNEMVTKVALADIRGALAI
GYDEGTWLVACYTATSVAAMAFAPWCAVTFSLRRFTLCAISLFTLLGVLCPFAPNYESLL
LLRTLQGLAGGALPPMLMTVALRFLPANVKLYGLAGYALTATFGPGLGTPLAGLWTEYVG
WQWTFWQIIAPCLIAMAAVAYGLPQDPLRLERFKSFNWRGVLLGFPAICMLVIGILQGNR
LDWFESNLICGLLGGGLLLLVLFLAGEWSQPIPFFKMQMLGIRNLSFALLTLAGVLVVLQ
AVIIIPSSYLAQVQGYRPVQTAPIMLLAALPQLIALPLVAALCNFRWVDCRWVLGIGLSM
LALSCVGGSQLTSAWIRDDFYVLQWLQIFGQPMAVLPLLMLSTGSINPMEGPFASAWFNT
VKGLSAVIATGVIEALTTARLHFHSTMLVDRLGNSPLAERDSTSLAHRLHEQAVVLTSSD
LYLCMAGIAVILILLIFWLPTRIYPPRAPT