Protein Info for PfGW456L13_3559 in Pseudomonas fluorescens GW456-L13

Annotation: DNA alkylation repair enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 PF08713: DNA_alkylation" amino acids 115 to 236 (122 residues), 28.4 bits, see alignment E=6.3e-11

Best Hits

Swiss-Prot: 42% identical to YHAZ_BACSU: Uncharacterized protein YhaZ (yhaZ) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 79% identity to pfo:Pfl01_3330)

Predicted SEED Role

"DNA alkylation repair enzyme"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QRT6 at UniProt or InterPro

Protein Sequence (365 amino acids)

>PfGW456L13_3559 DNA alkylation repair enzyme (Pseudomonas fluorescens GW456-L13)
MTDQPAPALKEIFNTERLSHIASEMTAVYPAFEAKRFLKLAQTGLADLSVMQRMARVSEC
LHAVLPLDYEASLQVLRALAPRLNSGFVSMCLPHYVASYGAHAFDQSMDALKYFTAFGSS
EFAIRHFLRSDLERSLKLMHAWSLDDNEHVRRLASEGCRPRLPWSFRLEPVQADPTLAAN
ILDNLKADTSLYVRKSVANHLNDITKDHPDWVLDLIEGWSLDNRHTAWIAKHALRSLIKQ
GNRRALAIIGAGGKPEVEIVDVKVEPPVIGLGEKITLSFAVKSTVQSSQRLVIDYAIDYV
KANGSTSAKVFKLKALTLPGNAIETVSRGQQIKELTTRRHYAGRHAVHIMVNGERLASTA
FVILA