Protein Info for PfGW456L13_3143 in Pseudomonas fluorescens GW456-L13

Annotation: Permeases of the major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 29 to 47 (19 residues), see Phobius details amino acids 53 to 76 (24 residues), see Phobius details amino acids 88 to 110 (23 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 195 to 216 (22 residues), see Phobius details amino acids 229 to 249 (21 residues), see Phobius details amino acids 260 to 278 (19 residues), see Phobius details amino acids 284 to 307 (24 residues), see Phobius details amino acids 318 to 339 (22 residues), see Phobius details amino acids 351 to 370 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 1 to 380 (380 residues), 172.6 bits, see alignment E=1.5e-54 PF07690: MFS_1" amino acids 3 to 336 (334 residues), 125.8 bits, see alignment E=1.9e-40 amino acids 239 to 379 (141 residues), 42.1 bits, see alignment E=5.4e-15

Best Hits

Swiss-Prot: 38% identical to YAAU_ECOLI: Putative metabolite transport protein YaaU (yaaU) from Escherichia coli (strain K12)

KEGG orthology group: K08368, MFS transporter, putative metabolite transport protein (inferred from 74% identity to pae:PA4187)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QRR6 at UniProt or InterPro

Protein Sequence (386 amino acids)

>PfGW456L13_3143 Permeases of the major facilitator superfamily (Pseudomonas fluorescens GW456-L13)
MIAASALMGVFFGGFIGGWLTDRLGRKKVYFVGPTLFIVCSLAQFWVESAPVLFALRFII
GLAVGIEYPVATSLLVEFLPKKQRGPRLAALTILWFAGAAFAYVVGTSILNVGGDDAWRY
ALASASVIGLLLLLLRVGTPESARWLLSKGREADAERVIKHVYGQHYSLRDLPEEPDQKK
TSFLDLLHSGYGKRLFFVSVFWSCSIIPVFAVYAFAPKVLLALNLKGEWASYGSMIITML
FVVGCVLATRLINTIGRRCMLIHSFLWSGLALLGLATFSHSNEVLVLFLFGAYAVFIGGA
QVLQLVYPNELFPTEIRAFAVGIGTSLSRVGAAVGTYLVPVSLQTLGIGNTMYVAAVVTF
IGLMAAWAMAPETRSLNLRDAAALSS