Protein Info for PfGW456L13_2719 in Pseudomonas fluorescens GW456-L13

Annotation: Multidrug resistance protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 transmembrane" amino acids 31 to 51 (21 residues), see Phobius details PF13533: Biotin_lipoyl_2" amino acids 67 to 114 (48 residues), 60.8 bits, see alignment 1.7e-20 PF16576: HlyD_D23" amino acids 67 to 309 (243 residues), 69.8 bits, see alignment E=4.1e-23 PF00529: CusB_dom_1" amino acids 167 to 360 (194 residues), 37.4 bits, see alignment E=4.1e-13 PF13437: HlyD_3" amino acids 233 to 312 (80 residues), 58.9 bits, see alignment E=1.5e-19

Best Hits

KEGG orthology group: K03543, multidrug resistance protein A (inferred from 73% identity to smk:Sinme_4330)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QKP2 at UniProt or InterPro

Protein Sequence (365 amino acids)

>PfGW456L13_2719 Multidrug resistance protein A (Pseudomonas fluorescens GW456-L13)
MNSLLDKAAIATSASSGTPVVVVRRSKRKTIGLLLCVAALMVVAVWGAMAFSSGVTSTDN
AYVRGDVTSLAAKVAGYVTAVEVRDNQAVRAGDVLFRIDDRDYRAKLAQAEANVSAAQAR
LTHVDAQIQLQHALIRQAEAQRRSASADMSLAAKTHDRSRKLIVSNAVSQALVDETGTAQ
SRAAASVSAASATVEAQQQRITVFVAEREAAVAAVSQAEAARDLARIDLEHTVVHAPVDG
VVGNRQVRLGRFVTPGVSLLDIVPVNDVWIVANFKETQLEHIRPGQPVRVTVDGYPDAAL
DGVVDSFAPGSGSAFSLLPPDNATGNFVRVVQRVPVKIRLAENPLPGRIVPGLSARVEVA
QGAGS