Protein Info for PfGW456L13_1712 in Pseudomonas fluorescens GW456-L13

Annotation: Permeases of the major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 transmembrane" amino acids 43 to 60 (18 residues), see Phobius details amino acids 69 to 90 (22 residues), see Phobius details amino acids 102 to 122 (21 residues), see Phobius details amino acids 128 to 154 (27 residues), see Phobius details amino acids 168 to 193 (26 residues), see Phobius details amino acids 205 to 223 (19 residues), see Phobius details amino acids 248 to 272 (25 residues), see Phobius details amino acids 292 to 312 (21 residues), see Phobius details amino acids 322 to 341 (20 residues), see Phobius details amino acids 347 to 371 (25 residues), see Phobius details amino acids 383 to 403 (21 residues), see Phobius details amino acids 414 to 433 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 31 to 240 (210 residues), 89.6 bits, see alignment E=2.2e-29 amino acids 266 to 444 (179 residues), 51.3 bits, see alignment E=8.9e-18 PF07690: MFS_1" amino acids 34 to 299 (266 residues), 46.2 bits, see alignment E=3.1e-16 amino acids 292 to 441 (150 residues), 48 bits, see alignment E=9.2e-17 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 36 to 427 (392 residues), 444.6 bits, see alignment E=1.8e-137

Best Hits

Swiss-Prot: 54% identical to YHJE_ECOLI: Inner membrane metabolite transport protein YhjE (yhjE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to pfo:Pfl01_1015)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QN39 at UniProt or InterPro

Protein Sequence (445 amino acids)

>PfGW456L13_1712 Permeases of the major facilitator superfamily (Pseudomonas fluorescens GW456-L13)
MTVRDNRMTTSTTYSDSTPAQPTNSATRVATASFIGTAIEFYDFYVYATAAALVIGPVFF
PQTSGTAQMLSAFLTFGIAFLARPLGSALFGHFGDRIGRKSTLVASLLLMGVCTTLIGVL
PGYDSIGAWAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKRAWFGMFPQLGPSIGF
LAANGLFLTLAVVLDDEQFRSWGWRIPFLLSAALVMVGLYVRLKLHETPVFANAMARQER
VKIPLFELFGQYWVPVLLGAGAMVVCYALFYISTVFSLSYGVATLGYSRETFLGLLCFAV
LFMAAATPLSAWASDRYGRKPVLIIGGVLAILSGFLMEPLLTQGSTWGVALFLCIELFLM
GVTFAPMGALLPELFPTHVRYTGASAAYNLGGIVGASAAPFFAQKLVAMGGLSYVGGYVS
AAAVLSLIAVLCLKETRHNDLNQVA