Protein Info for PfGW456L13_1337 in Pseudomonas fluorescens GW456-L13

Annotation: DedA protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 transmembrane" amino acids 25 to 47 (23 residues), see Phobius details amino acids 53 to 80 (28 residues), see Phobius details amino acids 127 to 145 (19 residues), see Phobius details amino acids 152 to 174 (23 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details PF09335: SNARE_assoc" amino acids 47 to 172 (126 residues), 78.7 bits, see alignment E=2.6e-26

Best Hits

Swiss-Prot: 58% identical to DEDA_ECO57: Protein DedA (dedA) from Escherichia coli O157:H7

KEGG orthology group: K03975, membrane-associated protein (inferred from 89% identity to pfl:PFL_5476)

Predicted SEED Role

"DedA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293PXV5 at UniProt or InterPro

Protein Sequence (218 amino acids)

>PfGW456L13_1337 DedA protein (Pseudomonas fluorescens GW456-L13)
MDFNPIDIVLHLDVYLDMLVTNYGAWIYAILFMVIFCETGLVVMPFLPGDSLLFIAGAVA
AGGGMDPVLLAGLLMLAAILGDSTNYIIGRTAGEKLFSNPDSKIFRRDYLQQTHDFYDKH
GGKTVTLARFLPIIRTFAPFVAGVGRMPYPRFFAFSVLGTLLWVGGLVTLGYFFGNVPFI
KKNLSLLVVGIILLSLVPMIIGMVRNRLAGSNSKAESR