Protein Info for PfGW456L13_1319 in Pseudomonas fluorescens GW456-L13

Annotation: Phosphatidylglycerophosphatase A (EC 3.1.3.27)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 167 transmembrane" amino acids 26 to 47 (22 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 100 to 123 (24 residues), see Phobius details amino acids 142 to 166 (25 residues), see Phobius details PF04608: PgpA" amino acids 25 to 162 (138 residues), 145.9 bits, see alignment E=4e-47

Best Hits

Swiss-Prot: 54% identical to PGPA_ECOLI: Phosphatidylglycerophosphatase A (pgpA) from Escherichia coli (strain K12)

KEGG orthology group: K01095, phosphatidylglycerophosphatase A [EC: 3.1.3.27] (inferred from 97% identity to pba:PSEBR_a5035)

MetaCyc: 54% identical to phosphatidylglycerophosphatase A (Escherichia coli K-12 substr. MG1655)
Phosphatidylglycerophosphatase. [EC: 3.1.3.27]

Predicted SEED Role

"Phosphatidylglycerophosphatase A (EC 3.1.3.27)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 3.1.3.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0F4TL88 at UniProt or InterPro

Protein Sequence (167 amino acids)

>PfGW456L13_1319 Phosphatidylglycerophosphatase A (EC 3.1.3.27) (Pseudomonas fluorescens GW456-L13)
VTDHPKQVPAEFVPPSVWRNPWHFLAFGFGSGTLPKAPGTWGSLVALPFIPLWQMLPDWG
YWLMLGITMLFGFWLCGKVADDLRVHDHEGIVWDEMVGMWITLWLVPEGWQWLLAGFLMF
RFFDILKPWPIRWIDRHVHGGVGIMLDDVLAGVFAWLAMQGLVWFFA