Protein Info for PP_5606 in Pseudomonas putida KT2440

Annotation: conserved exported protein of unknown function with YVTN beta-propeller repeat

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 658 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF10282: Lactonase" amino acids 197 to 371 (175 residues), 27.4 bits, see alignment E=3.1e-10 PF02239: Cytochrom_D1" amino acids 235 to 340 (106 residues), 34.9 bits, see alignment E=1e-12

Best Hits

KEGG orthology group: None (inferred from 99% identity to ppf:Pput_2282)

Predicted SEED Role

"Collagen triple helix repeat domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A140FWF7 at UniProt or InterPro

Protein Sequence (658 amino acids)

>PP_5606 conserved exported protein of unknown function with YVTN beta-propeller repeat (Pseudomonas putida KT2440)
MNKKTRPAYLGVVLGVALIGLGVAYEKLWCDPRELLQERGGSQALHRLSRDGVNVEFEAR
PLAGGELKEGGFANIRFKLSDQTSGQPLSGMAPGAWIDPAQSAPAGDREQSCKARVALFL
KSSIGARPLLDLNSYFLLMLNNDASLTVIDPTVSVGGVTSTMARIELPGRPMDWAATSDD
KQVFVSIPERGKVSVIDTETFTRVADLDAGDQPLRVALQPDQHRLWVGNNSSDPAKGGVT
VIDVPGRSAMKHFNTGTGHHEIAFSADSRYAYVSNRDSGTLSVIDIPEMRLAKTIKVGPH
PLSVSYSALSQAVYVVDGEEGSVRVFDARSHQLRHTVQAEQGLGPMRFSHDGRYGIVLNT
LENQALVIDASTDKLIHHIPVAAEPYQLTFTKGYAYVRGLASPKVSMINLASLGEGRSPI
VQGFEAGPAAPRQAGDLPLAQGLSVSRDDNSVFVVNPVDNTTYFYAEGMNAPMSGYNNRG
HQARAAIVVDRSLREVAPGVYGSTVKLPAAGKFDVAFLLNQPQIIHCFSTEVAAGASAGE
RKGARAEFIGLDQPLPQHSDFTARVRIVGDDGQPRLGLNDLSLRYFLAPSSMPRNLRLQE
VGEGVYQAALNLPEAGAWYLHVQSPSLGRKFAEENYTSLRVLPAAATNASQTDVRNVR