Protein Info for PP_5257 in Pseudomonas putida KT2440

Annotation: L-pipecolate oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01266: DAO
  • amino acids 34 to 385 (352 residues), 227.6 bits, E=8.6e-71
• PF13450: NAD_binding_8
  • amino acids 37 to 63 (27 residues), 22.2 bits, see alignment (E = 3.5e-08)

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_5257)

MetaCyc: 100% identical to pipecolate oxidase (Pseudomonas putida)
L-pipecolate oxidase. [EC: 1.5.3.7]

Predicted SEED Role

"L-pipecolate oxidase (1.5.3.7)" in subsystem Lysine degradation

MetaCyc Pathways

• L-lysine degradation V (9/9 steps found)
• L-lysine degradation II (L-pipecolate pathway) (5/9 steps found)
• superpathway of L-lysine degradation (23/43 steps found)

KEGG Metabolic Maps

• Lysine degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.3.7

Sequence Analysis Tools

See Q88CC4 at UniProt or InterPro

Protein Sequence (432 amino acids)

>PP_5257 L-pipecolate oxidase (Pseudomonas putida KT2440)
MEPAMSELRQQCLWEHVSKPTVAAQALAGEHKADVCVIGGGITGLSAAIHLLEQGKSVIV
LEAWKIGHGGSGRNVGLVNAGTWIRPDDVEATLGQKQGSRLNKVLGEAPAEVFAMIERLG
IDCQAQHKGTLHMAHNATGIADLEARHEQWRRRGADVELLTGAQCQEYCGTDKISAALLD
RRAGTINPMGYTQGLAAAVTRLGGKIFQQSSVEGLEREGDGWRVKTARGAVRAEKVVIST
GAYTEGDWSNLQKQFFRGYYYQVASKPLQGIAADKVLPHGQGSWDTRTVLSSIRRDDQGR
LLLGSLGRVDNKPAWFVRSWADRIQSHYYPELGKVEWEMHWTGCIDFTPDHLMRLFEPAP
GLVAVTGYNGRGNTTGTVIGRAFAEFLLKGEADSLPIPFSPMSGVSAPSLRTAFYESGFS
LYHAGQCLRVVL