Protein Info for PP_5111 in Pseudomonas putida KT2440

Annotation: Signal Recognition Particle protein translocation receptor GTPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 494 PF02881: SRP54_N" amino acids 206 to 271 (66 residues), 57.2 bits, see alignment E=3.3e-19 TIGR00064: signal recognition particle-docking protein FtsY" amino acids 220 to 490 (271 residues), 366.8 bits, see alignment E=3.4e-114 PF06414: Zeta_toxin" amino acids 285 to 396 (112 residues), 35.3 bits, see alignment E=1.6e-12 PF00448: SRP54" amino acids 290 to 490 (201 residues), 260.3 bits, see alignment E=2.2e-81

Best Hits

Swiss-Prot: 56% identical to FTSY_ECOLI: Signal recognition particle receptor FtsY (ftsY) from Escherichia coli (strain K12)

KEGG orthology group: K03110, fused signal recognition particle receptor (inferred from 100% identity to ppu:PP_5111)

Predicted SEED Role

"Signal recognition particle receptor protein FtsY (=alpha subunit) (TC 3.A.5.1.1)" in subsystem Bacterial Cell Division or Two cell division clusters relating to chromosome partitioning or Universal GTPases (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88CR9 at UniProt or InterPro

Protein Sequence (494 amino acids)

>PP_5111 Signal Recognition Particle protein translocation receptor GTPase (Pseudomonas putida KT2440)
MFGSNDDKKAPAEAGEKKGLFSWFRKKPQPPAGAGVPAHEPPAVEQSAAAPVEGSAAEAP
QAPEPVQAVAAPQLAEPQPVAAPPRPPVVEAPVPEPVASQPLQAPEPEPVASQPLVAPAP
QPVASMPLQAAPVESAPVEAAAPVSNLVLPVAEEPVALVPDLEPKAPPAIPERAAPAPVA
APVEQAKPGFFARLKQGLSKTSASIGEGMASLFLGKKVIDDDLLDEIETRLLTADVGVEA
TSAIVQNLTQKVARKQLADADALYKSLQEELAALLRPVEQPLNVQAQNKPYVILVVGVNG
AGKTTTIGKLAKKLQLEGKKVMLAAGDTFRAAAVEQLQVWGERNQIPVIAQHTGADSASV
IFDAVQAAKARGVDVLIADTAGRLHTKDNLMEELKKVRRVIGKLDVEAPHEVLLVLDAGT
GQNAISQAKYFNQSVELTGLALTKLDGTAKGGVIFALAKQFNIPIRFIGVGEGIDDLRTF
EAEPFVKALFAERD