Protein Info for PP_4814 in Pseudomonas putida KT2440

Annotation: ATP-dependent protease La domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 197 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF02190: LON_substr_bdg" amino acids 3 to 190 (188 residues), 99.1 bits, see alignment E=1.7e-32

Best Hits

KEGG orthology group: K07157, (no description) (inferred from 100% identity to ppf:Pput_4689)

Predicted SEED Role

"Uncharacterized protein, similar to the N-terminal domain of Lon protease" in subsystem Proteasome bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88DL1 at UniProt or InterPro

Protein Sequence (197 amino acids)

>PP_4814 ATP-dependent protease La domain protein (Pseudomonas putida KT2440)
MMTLPLFPLNTVLFPGCFLDLQIFEARYLDMIGRCMKQGEGFGVVCILEGDQVGKAPPVV
ASIGCEAVIRDFVQQDNGLLGIRVEGVRRFNLESSEVQKDQLLVGQVQWLPEQADSPLLE
ADDDLLALLVALGEHPMVEALGMPRPVDGRQALANQLAYLLPFMEEDKLDLLTLDSPQQR
LGEIQKLLERIQGELFA