Protein Info for PP_4765 in Pseudomonas putida KT2440

Annotation: conserved protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 412 PF03486: HI0933_like" amino acids 12 to 403 (392 residues), 253.2 bits, see alignment E=8.5e-79 TIGR00275: flavoprotein, HI0933 family" amino acids 13 to 403 (391 residues), 292.9 bits, see alignment E=3.4e-91 PF00890: FAD_binding_2" amino acids 13 to 62 (50 residues), 24.2 bits, see alignment 6.4e-09 PF13450: NAD_binding_8" amino acids 14 to 45 (32 residues), 28.1 bits, see alignment (E = 6.9e-10) TIGR03862: flavoprotein, TIGR03862 family" amino acids 32 to 410 (379 residues), 542.3 bits, see alignment E=5.1e-167 PF22780: HI0933_like_1st" amino acids 198 to 351 (154 residues), 113 bits, see alignment E=4.8e-36

Best Hits

KEGG orthology group: K07007, (no description) (inferred from 100% identity to ppu:PP_4765)

Predicted SEED Role

"NAD(FAD)-utilizing dehydrogenases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88DQ8 at UniProt or InterPro

Protein Sequence (412 amino acids)

>PP_4765 conserved protein of unknown function (Pseudomonas putida KT2440)
MPDLTPASPPPAVVIGGGPAGLMAAEALAKAGLAVEVFDAMPSVGRKFLLAGVGGMNITH
SEPYPAFVARYAERQGEIEALLRDFDADALRQWIHGLGIETFVGTSGRVFPTDMKAAPLL
RAWLKRLRDNGVVIHTRHRWLGWNTDGSLRIAYPQGERQVKASVVVLALGGASWARLGSD
GSWQPLLAERAVDISPLQPSNCGFEVAGWSALLKDKFAGAPLKNIALSVPGSAPRKGEFI
LTAQGVEGSLVYAWSAPVREAIHREGRGVLLLDLLPDKPVDKIAQALAKPRGSRSMAKHL
HSQLGIDGVKAALLRELTDQATFADVDALARAIKALPITLVRTRPLDEAISSAGGVRFEG
LDEGLMVKGMPGVFCAGEMLDWEAPTGGYLLTACFASGLRAGRAAADWVQAS