Protein Info for PP_4684 in Pseudomonas putida KT2440

Annotation: conserved protein of unknown function with kinase-like domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 520 PF01636: APH" amino acids 123 to 284 (162 residues), 29.7 bits, see alignment E=5.7e-11 PF13671: AAA_33" amino acids 338 to 486 (149 residues), 146.3 bits, see alignment E=8.2e-47

Best Hits

KEGG orthology group: K07028, (no description) (inferred from 98% identity to ppf:Pput_4548)

Predicted SEED Role

"FIG00955330: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88DY4 at UniProt or InterPro

Protein Sequence (520 amino acids)

>PP_4684 conserved protein of unknown function with kinase-like domain (Pseudomonas putida KT2440)
MSQALITALQNPALYPHPVEGFQLIETHISWVLLTGEYAYKIKKPMNFGFLDFTGLDQRQ
HFCNEELRLNQRLTEGLYLEVLPITGSVDAPQIGGEGEAIEYVLKMRQFPQGQMLNTLQA
NGELNATHIDQMARQIAEFHLQAPRVPMEHPLGTPESVMAPVEQNFEQIRPFLSDKADLQ
QLDALQAWARSSFERLQGLLEKRKANGFIRECHGDIHLGNATLIDGKVVIFDCIEFNEPF
RLTDVYADTAFLAMDLEDRGLKCLARRFISQYLELTGDYEGLELLNFYKAYRALVRAKVA
LFSMPADADGVQRATTLRTYRNYANLAESYSAIPSRLLAITHGVSAVGKSHVAMRLVEAL
GAVRVRSDVERKRLFGEQPQADAGQLSTGIYDQDASAATYQRLHEVAATVLRAGFPVVLD
ATYLKREQRQAAADVASQTGVPFLILDCHAPEAVIASWLEQRQAENSDPSDATLEVIKAQ
QASREALDAQELVHSTRVDTQAAGSMDQVIEQIRQRLPGL