Protein Info for PP_4676 in Pseudomonas putida KT2440

Annotation: methionine sulfoxide reductase catalytic subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 signal peptide" amino acids 32 to 52 (21 residues), see Phobius details PF00174: Oxidored_molyb" amino acids 118 to 275 (158 residues), 114.7 bits, see alignment E=1.8e-37

Best Hits

Swiss-Prot: 100% identical to MSRP_PSEPK: Protein-methionine-sulfoxide reductase catalytic subunit MsrP (msrP) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K07147, (no description) (inferred from 100% identity to ppu:PP_4676)

Predicted SEED Role

"Putative sulfite oxidase subunit YedY"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88DZ2 at UniProt or InterPro

Protein Sequence (341 amino acids)

>PP_4676 methionine sulfoxide reductase catalytic subunit (Pseudomonas putida KT2440)
MEPFMLIKLPRSSECKASEITPEGIYLSRRTLLGGSLAGLALGALPGGVGAAQMSRYADV
QAGAAPAWFTDKLAATRWQAVTVKDEAITPFKDATHYNNFYEFGPDKGDPAANGDSLKTE
PWSIVVDGEVRKPGRYALEDFVKPYQLEERIYRLRCVEAWSMVIPWLGFPLAQVLKQVEP
TSSARYVRFETLKDPQHMPGQRSGFALIDWPYREGLRLDEAMHPLAILAVGMYGRELPNQ
NGAPLRLVVPWKYGFKSIKSIVRISLVAEQPGTTWEGLAPDEYGFYANVNPTVDHPRWSQ
ARERRLPSGLFSPNVRETQMFNGYADEVASLYTGLDLRKNY