Protein Info for PP_4515 in Pseudomonas putida KT2440

Annotation: Transcriptional regulator, MarR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 145 PF12802: MarR_2" amino acids 33 to 92 (60 residues), 50.9 bits, see alignment E=2.2e-17 PF01047: MarR" amino acids 34 to 92 (59 residues), 40.7 bits, see alignment E=2.7e-14 PF09339: HTH_IclR" amino acids 41 to 84 (44 residues), 25.3 bits, see alignment E=1.6e-09

Best Hits

Swiss-Prot: 39% identical to SLYA_BLOFL: Transcriptional regulator SlyA (slyA) from Blochmannia floridanus

KEGG orthology group: K06075, MarR family transcriptional regulator, transcriptional regulator for hemolysin (inferred from 99% identity to ppf:Pput_1396)

Predicted SEED Role

"Transcriptional regulator SlyA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88EF0 at UniProt or InterPro

Protein Sequence (145 amino acids)

>PP_4515 Transcriptional regulator, MarR family (Pseudomonas putida KT2440)
MPLNDNQHRFGMQLAQMSRGWRAELDRRLAGLNLSQARWLVLLHLARFEEAPTQRELAQS
VGVEGPTLARLLDSLEAQGLVRRQAVLEDRRAKKIVLCPPAKPLIDQIETIANQLRVELF
TGVDEADLQVCMRVHAKILANLEKS