Protein Info for PP_4234 in Pseudomonas putida KT2440

Annotation: Aldehyde oxidase and xanthine dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 943 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 344 to 362 (19 residues), see Phobius details PF02738: MoCoBD_1" amino acids 265 to 484 (220 residues), 124.4 bits, see alignment E=4.4e-40 PF20256: MoCoBD_2" amino acids 516 to 600 (85 residues), 32.1 bits, see alignment E=8.8e-12 amino acids 761 to 881 (121 residues), 64.5 bits, see alignment E=1.2e-21

Best Hits

KEGG orthology group: None (inferred from 99% identity to ppf:Pput_1630)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A140FWL5 at UniProt or InterPro

Protein Sequence (943 amino acids)

>PP_4234 Aldehyde oxidase and xanthine dehydrogenase (Pseudomonas putida KT2440)
MSNRDISRRAFLQGGLIAGVGVTMAPLGSQAFAALMEERVTTSPQKWMNHDGKARFRNDA
LSKVCGDKVFARDIRAKDMPGWPAQQGHALLLKATKVDRIYAGHDLSLLGSDLQPDRIVT
AADLEQDGIAWPEAHSPDPLLPPGKVPMFIGYPVAILIWHDFERFRQAKRKLQFNQQAIR
YGAQAPLYQRDPYGSFRFVRVGGATPFDDDEFSSLKNSMLFPTILNRKPVWSKQPNQHGD
LTEQGLFYAKRMAEQLDNPPEDWLVFDERYKTPSIEPAALEPDNGNGWYDPATGTLHFVV
ATQCPFEVAQECVHMIKPSRFALNTLNMHPGYTVGYGSKDNNIFVFYAAVAALYGAGVPI
RLANDRYEQFQSGIKRHAFDIRYQLAVDKKDNSFKIFRADMSCDGGGRINYSPSVAAVGA
TAAQSIYYMPQNDLSVTAYYSRGVEAGSMRGYGTLQSMAATEMMVDEIAGRLGVDAIDLR
RANALKSGMKNTQGAVPAGALRLYEILDKAAVHEWWRNRDTRKQQMDAKDPDHWYGVGFA
ICQKDFGTGSEAPMASVEFSADGRISLRHIGTELGTGMSTSQALVVSDFLGRSADEVKTA
VTEWPELQLSTSGNPYLISQPEQDAALRNPRWVGKLASPSSATNSAFYFSHATREAARVL
FNHGLWPAAMAIWSQGPHGGQANPLVVRRENAVWVNGELTGNGLAPIPFAQLAQKAHDMG
LVTGVSVHGFNRWSWAEADFVIDGVRERFPLDAMAVKYGDGAVNAKKAQMGSHGYHLLDR
QNAAYPDTQLNNAMVTYYSPVATIVEVKVNKGTLETQVLNHHSWVECGRVLVPELVKGQL
EGGIAMGIGHALTEEMPLYEGGPGEGDWNFNRYRLPHARDVAVWQQTSEILPPLSPTDPS
KGIAEVVMIPVVGAIGNAVAHAIGKRVRDLPITPARIKEALNG