Protein Info for PP_3811 in Pseudomonas putida KT2440

Annotation: Transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 PF00126: HTH_1" amino acids 5 to 63 (59 residues), 77.7 bits, see alignment E=5.1e-26 PF03466: LysR_substrate" amino acids 88 to 291 (204 residues), 156.2 bits, see alignment E=8.2e-50

Best Hits

Swiss-Prot: 37% identical to Y1364_HAEIN: Uncharacterized HTH-type transcriptional regulator HI_1364 (HI_1364) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 100% identity to ppf:Pput_1959)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88GB3 at UniProt or InterPro

Protein Sequence (294 amino acids)

>PP_3811 Transcriptional regulator, LysR family (Pseudomonas putida KT2440)
MNPYEDMRIFAQVMEAGSFTAAADRLGMSKQSVSRRLMQLEERLGVRLLNRSTRRLDATP
LGQHYYQSALRLLGEVQQVEHDISGQAQVLRGTLRLSAPLSFAMAHLGCLLTEFLQLHPQ
VDVEVDLSDRAVDLIGEGYDLALRIGALEDSSLIARRIASVERVYCASPAYLQARGVPGK
PDELAAHDCLPYGHSRQVQWQFHKGGKTQAIQVTGRMRANNGELLRGAAIAGMGVTYLPT
FIVGQALAEGQLVTVLDEWRPPALQLSAVYPQHRQVARPVQGFVSFLRARLAQL