Protein Info for PP_3740 in Pseudomonas putida KT2440

Annotation: Major facilitator family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 56 to 76 (21 residues), see Phobius details amino acids 87 to 105 (19 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 148 to 169 (22 residues), see Phobius details amino acids 175 to 196 (22 residues), see Phobius details amino acids 255 to 274 (20 residues), see Phobius details amino acids 290 to 311 (22 residues), see Phobius details amino acids 320 to 338 (19 residues), see Phobius details amino acids 344 to 367 (24 residues), see Phobius details amino acids 379 to 400 (22 residues), see Phobius details amino acids 409 to 429 (21 residues), see Phobius details PF07690: MFS_1" amino acids 28 to 339 (312 residues), 144.9 bits, see alignment E=3.1e-46 PF00083: Sugar_tr" amino acids 55 to 424 (370 residues), 89.2 bits, see alignment E=2.8e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_3740)

Predicted SEED Role

"vannilate transporter VanK" in subsystem Phenylpropanoid compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88GI3 at UniProt or InterPro

Protein Sequence (446 amino acids)

>PP_3740 Major facilitator family transporter (Pseudomonas putida KT2440)
MNTDLKQRLDNDPMGRFQCLAIGICIILNMIDGFDVLVMAFTAASVSAEWGLNGAQVGLL
LSAGLFGMAAGSLFIAPWADRFGRRPLILLCLALSGIGMLLSALSQSPLQLALLRGLTGL
GIGGILASSNVIASEYASERWRGLAVSLQSTGYALGATLGGLLAVWLLGHWGWRSVFLFG
GVVTVLVIPLVLLWLPESLDFLLARRPANALARVNRLAVRLGQPALAQLPAVAARAEGAK
TGFRQLLAPAMRRTTLVIWLLFFLVMFGFYFVMSWTPKLLVAAGLSAQQGITGGVLLSVG
GIVGAALIGGLASRWPLTRVLALFMLITAALLVLFVANGASVTAALALGLLIGLFSNGCV
AGLYALSPVVYDASVRATGVGWGIGIGRMGAILSPTVAGVLLDGGWQPLHLYGVFASVFV
LAAGCLLLLRPTAKPASALPADALSH