Protein Info for PP_3579 in Pseudomonas putida KT2440

Annotation: conserved membrane protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 36 to 56 (21 residues), see Phobius details amino acids 76 to 97 (22 residues), see Phobius details amino acids 110 to 133 (24 residues), see Phobius details amino acids 189 to 213 (25 residues), see Phobius details PF07077: DUF1345" amino acids 34 to 204 (171 residues), 195.5 bits, see alignment E=3.1e-62

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppf:Pput_2192)

Predicted SEED Role

"Probable transmembrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88GY6 at UniProt or InterPro

Protein Sequence (215 amino acids)

>PP_3579 conserved membrane protein of unknown function (Pseudomonas putida KT2440)
MAFHRLTRTHPRLSLAAAVGLAGAWLIPAGDTVQHILAGWNLGVWLYLLLVLYLSWTASP
EKVRKVAGVEDENAGLVLLTVCIAAIASLAAVTLQLVSSRGLQGTALAVHYLYTGLTVAG
SWLLIGCIFTLHYARLFYTGQNHEPPLRFADGERNPDYWDFHYFSFTISVAVQTSDVGVA
GRGLRRVVLAHSLVGFVFNTAILGFTINIAAGLLG