Protein Info for PP_3103 in Pseudomonas putida KT2440

Annotation: conserved protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 transmembrane" amino acids 6 to 33 (28 residues), see Phobius details amino acids 91 to 108 (18 residues), see Phobius details PF21724: DUF6861" amino acids 4 to 143 (140 residues), 121 bits, see alignment E=4.4e-39 PF15538: Ntox46" amino acids 193 to 349 (157 residues), 323.6 bits, see alignment E=2.1e-101

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_3103)

Predicted SEED Role

"FIG00964744: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88I96 at UniProt or InterPro

Protein Sequence (357 amino acids)

>PP_3103 conserved protein of unknown function (Pseudomonas putida KT2440)
MWWPGAVAGAGIGLQVGNLILMGLGLSAIAEYFYQGLPACLSTLQQGMATAWFAEDGLKP
AGLDPSGGSAAQAQERVERAARQLARGQEQLVLLLLTAIVTYLTRGQMKAGVMSSMESIA
ARSARLQAEISNKQLAAWLAKNEQKLLAQPELQPKEATPISRAQAQPEPLRPLPDRPPIA
QAPDKPGLTEVSRREHLNKKFARTGNLAQDINIRGNQETAVNFFKSQGYKPADYEGYMNG
LDFTQPVFTETINRGKTLWQFQVPGGRQGMWYSPTPDVVPGQLGINPLGQIFKTETIVPK
IVNVYQSTEKVTLLRSTSAPVLDTWSVPSQPYNAIGGARQMTSAQRELFKLITPGAL