Protein Info for PP_2955 in Pseudomonas putida KT2440

Annotation: Magnesium/cobalt transporter, CorA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 transmembrane" amino acids 246 to 265 (20 residues), see Phobius details amino acids 277 to 299 (23 residues), see Phobius details PF01544: CorA" amino acids 23 to 301 (279 residues), 97.7 bits, see alignment E=4e-32

Best Hits

KEGG orthology group: K03284, metal ion transporter, MIT family (inferred from 100% identity to ppu:PP_2955)

Predicted SEED Role

"Magnesium and cobalt transport protein CorA" in subsystem Campylobacter Iron Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88IP4 at UniProt or InterPro

Protein Sequence (303 amino acids)

>PP_2955 Magnesium/cobalt transporter, CorA family (Pseudomonas putida KT2440)
MIEYYLAVDGALLEAPEERASVWLCVAPDATEQSRLCECLGVSAQSLESSLDPDEVARIE
IKPDHLFLIWKRPESFDGRVFNVSSFGVVLSEKRLVVICAANSLLAGVDRQAGMSTPLDV
LMAMLAESVHHYLGHLRVVKQVAREIQLQFDRSMDNQHLVQMYSLSESLVYYVNAIQSNG
AVLALLRSHGQKHGFGPKQLEMLNDLIIENEQSYQQAKIHAQVFTNLIEARGNLANNGMN
HALRNLTMINVVFLPLNLLASIGGMSEFSMMTAGMPWWLTFPTLLLAMAVLGGAMAVALR
RMA