Protein Info for PP_2949 in Pseudomonas putida KT2440

Annotation: putative permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 transmembrane" amino acids 7 to 29 (23 residues), see Phobius details amino acids 35 to 56 (22 residues), see Phobius details amino acids 68 to 88 (21 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 122 to 140 (19 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details amino acids 212 to 232 (21 residues), see Phobius details amino acids 239 to 261 (23 residues), see Phobius details amino acids 267 to 284 (18 residues), see Phobius details PF00892: EamA" amino acids 7 to 129 (123 residues), 52.5 bits, see alignment E=3.3e-18 amino acids 149 to 282 (134 residues), 53.9 bits, see alignment E=1.2e-18

Best Hits

Swiss-Prot: 64% identical to YDEK_BACSU: Uncharacterized transporter YdeK (ydeK) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to ppu:PP_2949)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88IQ0 at UniProt or InterPro

Protein Sequence (288 amino acids)

>PP_2949 putative permease (Pseudomonas putida KT2440)
MEKSATGWINGFIGVAIFAGSLPATRVAVADFEPTFLTCARATIAAMLGALFLIVLRQPR
PKRRDLSPLAVTALGVVIGFPLLTAFALQHISSAHSIVFVGLLPLCTAGFAVLRGGERPR
PLFWLFSLTGAGLVAGYALMNGGEASAVGDLLMLAAVVVCGLGYAEGARLSRTLGGWQVI
SWALLVALPFMLLLTVVNLPAPDDFARVSAPAWFSFGYVSLFSMLIGFVFWYRGLVQGGI
AAVGQLQLFQPFMGLGLAALLLHEHVSWTMLLVTLGAVICVYGARKYA