Protein Info for PP_2867 in Pseudomonas putida KT2440

Annotation: Pyridine nucleotide-disulphide oxidoreductase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF07992: Pyr_redox_2
  • amino acids 3 to 311 (309 residues), 150.8 bits, E=1.2e-47
• PF00070: Pyr_redox
  • amino acids 154 to 230 (77 residues), 25.5 bits, E=3.1e-09

Best Hits

KEGG orthology group: K03885, NADH dehydrogenase [EC: 1.6.99.3] (inferred from 100% identity to ppu:PP_2867)

Predicted SEED Role

"NADH dehydrogenase (EC 1.6.99.3)" in subsystem Carboxysome or Respiratory dehydrogenases 1 (EC 1.6.99.3)

MetaCyc Pathways

• aerobic respiration III (alternative oxidase pathway) (3/3 steps found)
• NADH to cytochrome bo oxidase electron transfer I (2/2 steps found)
• aerobic respiration I (cytochrome c) (3/4 steps found)
• NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
• Fe(II) oxidation (3/6 steps found)
• NAD(P)/NADPH interconversion (3/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.99.3

Use Curated BLAST to search for 1.6.99.3

Sequence Analysis Tools

See Q88IY2 at UniProt or InterPro

Protein Sequence (400 amino acids)

>PP_2867 Pyridine nucleotide-disulphide oxidoreductase family protein (Pseudomonas putida KT2440)
MKQILIIGAGFAGLWSALSAIRQLDLNGSKGVEVTLLAPQAELHVRPRFYEPDVHTMAAP
LQALFDAVNVRFVQGTAYHIDEAARRVGYRTRSGTRCTLPYDRLIMACGSELERPDMVGI
EHAFDVDKLDSAARLEAHLKSLASLPNTPARNTVVVAGGGFTGIETATELPARLRAILGE
DAALRIVVIDRGARIGAALGDGIRPAIEQACEALGVEWVCGATVVSVDPAGVQLDNGQRI
DASTVVWTVGFKANPLTEQISGERDNRGRLHVDGNLKVKGNDAVYAAGDVAYATCDELGN
HAVMSCQHAIALGRHAGNNAAAELLGVAPTAYSQPKYVTCLDLGAWGAVYTEGWDREVSP
PEDKAEAKALKRQINSVWIYPPAADRASALAAADPLIPVA