Protein Info for PP_2862 in Pseudomonas putida KT2440

Annotation: Undecaprenyl-diphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 45 to 64 (20 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 109 to 130 (22 residues), see Phobius details amino acids 188 to 206 (19 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 251 to 269 (19 residues), see Phobius details TIGR00753: undecaprenyl-diphosphatase UppP" amino acids 10 to 258 (249 residues), 265.5 bits, see alignment E=2.7e-83 PF02673: BacA" amino acids 10 to 259 (250 residues), 286.4 bits, see alignment E=1.3e-89

Best Hits

Swiss-Prot: 100% identical to UPPP_PSEPK: Undecaprenyl-diphosphatase (uppP) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K06153, undecaprenyl-diphosphatase [EC: 3.6.1.27] (inferred from 100% identity to ppu:PP_2862)

Predicted SEED Role

"Undecaprenyl-diphosphatase (EC 3.6.1.27)" (EC 3.6.1.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88IY7 at UniProt or InterPro

Protein Sequence (277 amino acids)

>PP_2862 Undecaprenyl-diphosphatase (Pseudomonas putida KT2440)
MMDFWTAFQAIILGVVEGLTEFLPISSTGHQIIVADLIGFGGERAMAFNIIIQLAAILAV
VWEFRSKIFEVVFGLTNQPKARRFTGNLLLAFMPAVVLGVLFADLIHEYLFNPVTVAAAL
VVGGVIMLWAERREHRVEVDHVDDMRWSHALKIGFIQCLAMIPGTSRSGSTIIGGLLFGL
SRKAATEFSFFLAMPTMVGAAVYSGYKYRDLFQPGDLPVFALGFVTSFIFAMIAVRALLK
FIANHSYAAFAWYRIVFGLFILATWQFGWVDWSTAHG