Protein Info for PP_2861 in Pseudomonas putida KT2440

Annotation: Methyl-accepting chemotaxis transducer

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 193 to 215 (23 residues), see Phobius details PF08269: dCache_2" amino acids 39 to 190 (152 residues), 123.7 bits, see alignment E=2.2e-39 PF17200: sCache_2" amino acids 41 to 191 (151 residues), 124.8 bits, see alignment E=7e-40 PF17201: Cache_3-Cache_2" amino acids 102 to 186 (85 residues), 35.3 bits, see alignment E=2.1e-12 PF00672: HAMP" amino acids 210 to 258 (49 residues), 46.3 bits, see alignment 1.1e-15 PF00015: MCPsignal" amino acids 356 to 507 (152 residues), 140.7 bits, see alignment E=1.1e-44

Best Hits

Swiss-Prot: 100% identical to MCPP_PSEPK: Methyl-accepting chemotaxis protein McpP (mcpP) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to ppu:PP_2861)

Predicted SEED Role

"Methyl-accepting chemotaxis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88IY8 at UniProt or InterPro

Protein Sequence (544 amino acids)

>PP_2861 Methyl-accepting chemotaxis transducer (Pseudomonas putida KT2440)
MNTLRSMSISRRLWLILVVAVAMLVVLGLLMLRQIHGDLYQAKAEKTRHVVQTAAGVLAY
YQGLEAAGTLSREAAQQQALQVVRALRYDHDDYFWINDLGPKMIMHPANPKLDDQDLSAI
RDPDGFAVFNEMVALARQQDAGPVNYRWPKPGASEPVAKTSYIQLFKPWGWIIGSGVYVD
DVQAEFARQLRDASLVGVGIALLMALVVMLIARSIARPLQEAVQAMGNIASGESDLTRRL
DTHGSDEITHLGEHFNRFNGKLQGVVGQLQGAAHALAQSAGHVGDNAGAAQQRSAQQSLQ
MDQVATAVNEVTYAVQDVAKTAEQAAGEMRTAQQQVTHGQQAIHGSLAQIDRLSLTIDEA
VQVIRDLAGHSTRIGGVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRLLA
QRTAQSTAEIHTMIEHLQSQSDAAVKAIDTSSEASRQTVEQAREAGASLDAINQVLNNLT
ALNASIASATLQQSHVVEEINRNVLDTAGLSQQTADAARQSSDAGVALGRLSEELEQLLR
QFRV