Protein Info for PP_2849 in Pseudomonas putida KT2440

Annotation: urease accessory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 TIGR00101: urease accessory protein UreG" amino acids 8 to 199 (192 residues), 334.8 bits, see alignment E=8.9e-105 PF02492: cobW" amino acids 10 to 179 (170 residues), 153.9 bits, see alignment E=1.8e-49

Best Hits

Swiss-Prot: 100% identical to UREG_PSEPG: Urease accessory protein UreG (ureG) from Pseudomonas putida (strain GB-1)

KEGG orthology group: K03189, urease accessory protein (inferred from 98% identity to pen:PSEEN2100)

MetaCyc: 65% identical to urease accessory protein GTPase UreG (Helicobacter pylori 26695)

Predicted SEED Role

"Urease accessory protein UreG" in subsystem Urea decomposition

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88J00 at UniProt or InterPro

Protein Sequence (207 amino acids)

>PP_2849 urease accessory protein (Pseudomonas putida KT2440)
MQSYQQPLRVGVGGPVGSGKTALLEALCKAMRDHYQIAVVTNDIYTKEDQRILTEAGALE
PERIVGVETGGCPHTAIREDASMNLAAVEALARKFGNLEVIFVESGGDNLSATFSPELAD
LTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVGASLEVMERDTQRMRPQRPWT
FSNLKKGEGLQAVIDFIVERGMLGVRG