Protein Info for PP_2802 in Pseudomonas putida KT2440

Annotation: Amino acid permease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 transmembrane" amino acids 18 to 39 (22 residues), see Phobius details amino acids 48 to 69 (22 residues), see Phobius details amino acids 90 to 112 (23 residues), see Phobius details amino acids 126 to 145 (20 residues), see Phobius details amino acids 153 to 175 (23 residues), see Phobius details amino acids 195 to 213 (19 residues), see Phobius details amino acids 233 to 254 (22 residues), see Phobius details amino acids 279 to 310 (32 residues), see Phobius details amino acids 331 to 351 (21 residues), see Phobius details amino acids 357 to 375 (19 residues), see Phobius details amino acids 387 to 406 (20 residues), see Phobius details amino acids 412 to 429 (18 residues), see Phobius details PF13520: AA_permease_2" amino acids 22 to 405 (384 residues), 116.6 bits, see alignment E=1.4e-37 PF00324: AA_permease" amino acids 31 to 374 (344 residues), 134.1 bits, see alignment E=6.1e-43

Best Hits

Swiss-Prot: 39% identical to PLAP_ECO57: Low-affinity putrescine importer PlaP (plaP) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 100% identity to ppu:PP_2802)

MetaCyc: 39% identical to putrescine:H+ symporter PlaP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-69

Predicted SEED Role

"amino acid permease family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88J47 at UniProt or InterPro

Protein Sequence (443 amino acids)

>PP_2802 Amino acid permease family protein (Pseudomonas putida KT2440)
MSQSTSGASLRRSLGPFSVLLFGLAFLAPLIVFGTYGVITQASGNTTAMAYLVAATGVVF
TALSYGRLVRVFPVAGSAYTYTRKMLNANLGFMVGWAALLDYFFIPMLIWLLGASYLNMA
FPEVPQWVWITGFIVSTSLLNVLGIQVANRFNVLLMVVQLVIIAVFIGLCVHYIVAANGP
GGLLSAKPFFNQDVPFATSMAGAAIAAYSFLGFDALSTLSEETRDPGRTLPRAILLVALI
GGSVYVGSSYFMYLAHPSPTFELVDGAAFEIARMIGGDLFFAVVLTGIIVAHFAAGMSFQ
ASVGRLLYALGRDNQLPRRLFGALHPRYKTPAFNILLCGVFGTAGFGLTIATATSLVNFG
AFLAFTAVNLCALRLTFDARVKDGAGLLRGVLFPLIGLVTAGWMLVSLDKDALIMGGCWL
GLGLVYLACRTSLFRNPVPDALV