Protein Info for PP_2775 in Pseudomonas putida KT2440

Annotation: putative glycine betaine/L-proline ABC transporter, periplasmic component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF04069: OpuAC" amino acids 28 to 328 (301 residues), 180.6 bits, see alignment E=2.3e-57

Best Hits

KEGG orthology group: K02002, glycine betaine/proline transport system substrate-binding protein (inferred from 100% identity to ppu:PP_2775)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88J74 at UniProt or InterPro

Protein Sequence (348 amino acids)

>PP_2775 putative glycine betaine/L-proline ABC transporter, periplasmic component (Pseudomonas putida KT2440)
MTRFLSRGLAGFALLAALVPATASFAKDKIVIGEQNWTGAIAIQYILGDIISNRLDGEVS
YLAGDLPILFAAAAKGDGSVDVLTDIWLPNQSAAFAKYVTGGTHSLIPNKQPYVGVQGFY
IPGYIQDKYNVKSVYDLKKPEVAKLFAPLGGGKSQLLVGPAGWESTYIGQIKAKDFGFDG
NFESVSTEASVTYAKLDAAYKAERGVIFYAYTPDWIFSAYDLRRLDEPPFDGYAQDNKKG
DPLYKADGCWKFISPTVDADWLNKSSITCAYPDAKVHILASSALRQRAPRIAAFLENVSI
DPASLNDLILKIEREKQPADAAAKAWVAANQATVDRWLSATGTQVAAQ