Protein Info for PP_2563 in Pseudomonas putida KT2440
Annotation: putative Antibiotic biosynthesis protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to ppu:PP_2563)Predicted SEED Role
"L-aminoadipate-semialdehyde dehydrogenase large subunit (EC 1.2.1.31)" in subsystem Lysine degradation (EC 1.2.1.31)
MetaCyc Pathways
- L-lysine degradation V (9/9 steps found)
- L-lysine degradation VI (2/3 steps found)
- L-lysine degradation IX (1/2 steps found)
- L-lysine degradation VIII (1/2 steps found)
- L-lysine degradation II (L-pipecolate pathway) (5/9 steps found)
- L-lysine degradation XI (2/5 steps found)
- superpathway of L-lysine degradation (23/43 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.2.1.31
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q88JT4 at UniProt or InterPro
Protein Sequence (923 amino acids)
>PP_2563 putative Antibiotic biosynthesis protein (Pseudomonas putida KT2440) MPDLRPNPTLCLEYRAEQPIHHAFIQQASRCPAAIAIIGQHATCSYSQLEQISAGIAAFL VKNAASGTDRVVIVSRRSAALVYAMLGCLRAGLAFTVADAAYPAARIEQIVNTLKPAVIL RCAEASVDVGQPMVVTVPEALAEALQAFPRQPVALPAVSPEQPAYITFTSGSTGEPKGIV THHAPLVHFIDWHVRQHGFTQADTFSLLSGLGHDPVYRDVFTPLSLGATIACPAQSTLTE PSRLASWLHQHGVSVIHLTPPLGKLIETGAHLNGQILDHLRYLFWGGDALSPTQYQQVRA IAPNAVNVNFYGTTETPQAMAFHTLDPEMDNARVPLGKGIADAQLLVINPANQLVSEGET GEILIRSPYLSRGYWDDPGLTEAKFIANPFTADTADRCYRTGDLGTYLADGSARFLGRAD SQVKIRGHRIELAEIENAICRHPHIGQCVVLTNHEGASTRLVAYCVAQQAIRADELRQAL SGQLPDYMVPALFVFLDALPLTPNAKVDKRALPAAFDDSINPPLSPLAEKLSTAWARILQ VPRLDARLSFVELGGDSLSFVQASRVLEALIGHLPERWETLPVCQLAELSAPPKGAWRVM EMPVFIRMLAIILIVVGHLGDFDHWPILGETSVLFLVSGIALARFQLKAIEARGDARTLL RPLTAIVVPTLLYSALIQLVFARLHWQSLLLVSNWFPASEVSLFNYWYIEVLVQMIVIIG LVLSIRRVRQVLIADPFRWLIIAACALVALDVLLNQFVFDASALLNRVPQHFLAVMVLGM AVHHADTISRKWVASAVAVLVVGELDLMALAGVGWQAFTHYVDIALPAMLALVWFRSVPV PALVARAGAVIASSTLYIYLTHFQFESVAEHVFRHPLFEIALALAGGVLVSYCWNTLLRL LFTRRRKQHQARGADPAERATSA