Protein Info for PP_2543 in Pseudomonas putida KT2440

Annotation: gamma-aminobutyrate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 transmembrane" amino acids 27 to 48 (22 residues), see Phobius details amino acids 54 to 73 (20 residues), see Phobius details amino acids 94 to 116 (23 residues), see Phobius details amino acids 132 to 152 (21 residues), see Phobius details amino acids 163 to 186 (24 residues), see Phobius details amino acids 206 to 228 (23 residues), see Phobius details amino acids 248 to 269 (22 residues), see Phobius details amino acids 296 to 317 (22 residues), see Phobius details amino acids 343 to 363 (21 residues), see Phobius details amino acids 375 to 394 (20 residues), see Phobius details amino acids 414 to 436 (23 residues), see Phobius details amino acids 442 to 460 (19 residues), see Phobius details PF03845: Spore_permease" amino acids 24 to 265 (242 residues), 31.9 bits, see alignment E=1e-11 PF00324: AA_permease" amino acids 26 to 459 (434 residues), 381.9 bits, see alignment E=6.7e-118 PF13520: AA_permease_2" amino acids 27 to 456 (430 residues), 122.5 bits, see alignment E=3.3e-39

Best Hits

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 100% identity to ppg:PputGB1_2038)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88JV4 at UniProt or InterPro

Protein Sequence (470 amino acids)

>PP_2543 gamma-aminobutyrate permease (Pseudomonas putida KT2440)
MDATSTTTTAKSGHESKLSASLKSRHLTMMSIAGVIGGALFVGSGSVIHSAGPAAVLAYL
AGGILVVLIMRMLGEMATSSPDTGSFSTYADRAIGRWAGFTIGWLYWWYWVILMAWEAYV
AGKILHGFFPDVSVNVFVLATTLLLITVNFFNVKHYGEFEFWFALIKVIAIVCFLIVCTA
AVMNIWQFGEVRGISHLTAEGFMPNGITTVIGALLGVMFAFLGAEIVTIAASEAKDPAAQ
IVKATNSVVWRVCLFYVGSIFLIVCLVPWNDPHLGVSGYGAYRRTLELLGVPYAELLMNF
VVLTSVSSCLISGHYTASRMLFSLAQRGDAPSFFKITRAGTGVPVYAIMGSCAVAVVCAL
INFSETLRPKDVLDTLMNTTGMIALLVYLVIAFSQLRMRRKLIAEGKEVRLKMWLFPWLT
YLVIAFIVAALVTMAFMPDYQILVISTGIAAAVVVAMGVVHQIRSGSKQH