Protein Info for PP_2442 in Pseudomonas putida KT2440

Annotation: conserved protein of unknown function, DUF480 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 PF04337: DUF480" amino acids 13 to 156 (144 residues), 187.5 bits, see alignment E=7.4e-60

Best Hits

Swiss-Prot: 100% identical to Y2442_PSEPK: UPF0502 protein PP_2442 (PP_2442) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K09915, hypothetical protein (inferred from 100% identity to ppu:PP_2442)

Predicted SEED Role

"Virulence factor mviM"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88K50 at UniProt or InterPro

Protein Sequence (215 amino acids)

>PP_2442 conserved protein of unknown function, DUF480 family (Pseudomonas putida KT2440)
MSEHETAGEGRFNSIEIRVLGSLIEKQATSPESYPLTLNALVLACNQKTSREPVMNLTQG
QVGQALRALEGQGMTRLQMGSRADRWEHRVDKALELVPAQLVLMGLMFLRGPQTLNELLT
RSNRLHDFDDTEQIQHQLERLISRDLALHLPRQAGQREDRYTHALGDPAEIEAILAARQQ
EGGARTSGGSVSEDRIEALEARIAALEARLAELEG