Protein Info for PP_2367 in Pseudomonas putida KT2440

Annotation: putative inner membrane transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 395 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details transmembrane" amino acids 49 to 69 (21 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 106 to 127 (22 residues), see Phobius details amino acids 135 to 157 (23 residues), see Phobius details amino acids 163 to 185 (23 residues), see Phobius details amino acids 206 to 229 (24 residues), see Phobius details amino acids 242 to 261 (20 residues), see Phobius details amino acids 273 to 291 (19 residues), see Phobius details amino acids 297 to 316 (20 residues), see Phobius details amino acids 333 to 354 (22 residues), see Phobius details amino acids 360 to 380 (21 residues), see Phobius details PF07690: MFS_1" amino acids 15 to 334 (320 residues), 129.6 bits, see alignment E=1.4e-41 PF00083: Sugar_tr" amino acids 47 to 186 (140 residues), 28.9 bits, see alignment E=5.8e-11

Best Hits

Swiss-Prot: 68% identical to YDHP_ECOLI: Inner membrane transport protein YdhP (ydhP) from Escherichia coli (strain K12)

KEGG orthology group: K08156, MFS transporter, DHA1 family, arabinose polymer transporter (inferred from 100% identity to ppf:Pput_3328)

Predicted SEED Role

"Putative drug efflux protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88KC3 at UniProt or InterPro

Protein Sequence (395 amino acids)

>PP_2367 putative inner membrane transport protein (Pseudomonas putida KT2440)
MTAQTMRPGRVLFALAIGAFGIGTTEFTPMGLLPVIAQGVEVSIPSAGMLITAYAIGVMV
GAPIMTLLFSRFGKRAALMALMAIFTLGNLLSSLSPDYYTLLASRLVTSLNHGAFFGLGA
VVAASVVPKEKQASAVATMFMGLTIANIGGVPAATWIGQQIGWRMAFAGTAVLGLLAMAA
LWYALPKGERGSVPHVRKELAVIARPSVLLAMATTVLGAGAMFTLYTYVAPVLAELTGAS
DGFVTLGLVLIGVGFTLGNSLGGRLADWSLDGAAKIFLAVLALIMLAMPLVLGSHIGAAI
ALLVWGMFTFAVVPPLQMRVMTAAIEAPGLASSINVGAFNLGNAVGAALGGAVISLNLGY
AAVPMAGGVLAAAGLLLVWLGGRHKVAGKTAADMA