Protein Info for PP_2230 in Pseudomonas putida KT2440

Annotation: putative K(+)/H(+) antiporter subunit A/B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 971 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 27 to 47 (21 residues), see Phobius details amino acids 55 to 71 (17 residues), see Phobius details amino acids 77 to 97 (21 residues), see Phobius details amino acids 108 to 127 (20 residues), see Phobius details amino acids 132 to 150 (19 residues), see Phobius details amino acids 162 to 184 (23 residues), see Phobius details amino acids 204 to 222 (19 residues), see Phobius details amino acids 242 to 264 (23 residues), see Phobius details amino acids 270 to 291 (22 residues), see Phobius details amino acids 298 to 316 (19 residues), see Phobius details amino acids 322 to 344 (23 residues), see Phobius details amino acids 364 to 385 (22 residues), see Phobius details amino acids 405 to 427 (23 residues), see Phobius details amino acids 459 to 484 (26 residues), see Phobius details amino acids 502 to 523 (22 residues), see Phobius details amino acids 574 to 594 (21 residues), see Phobius details amino acids 605 to 624 (20 residues), see Phobius details amino acids 631 to 651 (21 residues), see Phobius details amino acids 657 to 678 (22 residues), see Phobius details amino acids 703 to 721 (19 residues), see Phobius details amino acids 759 to 777 (19 residues), see Phobius details amino acids 815 to 840 (26 residues), see Phobius details amino acids 849 to 868 (20 residues), see Phobius details amino acids 885 to 907 (23 residues), see Phobius details amino acids 927 to 949 (23 residues), see Phobius details PF00662: Proton_antipo_N" amino acids 64 to 110 (47 residues), 31.9 bits, see alignment 2.6e-11 PF00361: Proton_antipo_M" amino acids 126 to 404 (279 residues), 210.2 bits, see alignment E=1e-65 PF13244: MbhD" amino acids 615 to 680 (66 residues), 71.7 bits, see alignment 1.1e-23 PF20501: MbhE" amino acids 697 to 794 (98 residues), 151.5 bits, see alignment E=1.5e-48 PF04039: MnhB" amino acids 822 to 943 (122 residues), 125.5 bits, see alignment E=4e-40

Best Hits

KEGG orthology group: K05559, multicomponent K+:H+ antiporter subunit A (inferred from 72% identity to aaa:Acav_1966)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88KR0 at UniProt or InterPro

Protein Sequence (971 amino acids)

>PP_2230 putative K(+)/H(+) antiporter subunit A/B (Pseudomonas putida KT2440)
MSLIVLLLLPFVGSCLAAVLPHNARNAESILAGLVALVGTVQVALLYPQVAHGGVIREEF
LWLPSLGMNLVLRMDGFAWLFSLLVLGIGALVSLYARYYMSPQDPVPRFFAFFLAFMGAM
LGLVISGNLIQLVFFWELTSLFSFLLIGYWHHRADARRGAYMALMVTGAGGLCLLVGALL
LGHVVGSYDLDKVLAAGHIIRQHALYPVLLPLILIGALTKSAQFPFQFWLPHAMAAPTPV
SAYLHSATMVKAGVFLLARLWPVLSGSEEWFWIVGGAGALTLLLGAFAAMFQNDLKGLLA
YSTISHLGLITLLLGLNSPLAAVAAVFHILNHATFKASLFMAAGIIDHESGTRDIRRLSG
LIRLVPYTATLAMVASASMAGVPLMNGFLSKEMFFAETVFISSTAWVEATLPVIATLAGT
FSVAYALRFTVDVFFGPTAQDLPHTPHEPPRWMRAPVELLVLTCLVVGIFPTQSVGPLLA
AAALPVVGGTLPEYSLAIWHGWNAPMIMSLVAMSGGIVLYLLLRKQLRLGRFPYPPVIER
FNGKRLFEHGQVHLMLLARRIERVLTTRRLQSQLFMLVFAAFLAGLTPMLYSGLSWGDRP
KIPGSGVFVALWLIAIACAIGAAYQAKYHRLAALIMVSVCGLMTCITFVWFSAPDLALTQ
LVVEVVTTVLILLGLRWLPRRIEGVSPLPGSLERARLRRLRDLLLAVLVGGGMAVLSYAM
LTRPTPNDISSFYLSRALPQGGGTNVVNVMLVDFRGFDTLGEITVLVAVALTVFALLRRF
RPPKESMQLPAQQRQLAPDVVTDLINPRHATDTALGFMMVPAALVRLLLPIALLVSMYLF
MRGHNQPGGGFVAGLVMSVAFILQYMVAGTQWVEAQMSLRPLRWMGTGLLCATLTGVGAM
LLGYPFLTTHTAHLHLPLLGDVHVASALFFDIGVYTVVVGSTLLILTALAHQSVRAYRPG
NPAKTSQAGAA