Protein Info for PP_2202 in Pseudomonas putida KT2440

Annotation: conserved membrane protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 145 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 38 to 59 (22 residues), see Phobius details amino acids 91 to 112 (22 residues), see Phobius details amino acids 118 to 142 (25 residues), see Phobius details PF09335: VTT_dom" amino acids 24 to 137 (114 residues), 50.6 bits, see alignment E=1.4e-17

Best Hits

KEGG orthology group: None (inferred from 99% identity to ppf:Pput_3535)

Predicted SEED Role

"probable membrane protein YPO3302"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88KT7 at UniProt or InterPro

Protein Sequence (145 amino acids)

>PP_2202 conserved membrane protein of unknown function (Pseudomonas putida KT2440)
MLSLGALFLSAFGAATLLPLQSEAVLVGLLLRQPEAWATLLLVATLGNVLGSVVNWLLGR
AIEHLRDKRWFPFSAAQLARAQQRYQRWGQWSLLLSWMPVIGDPLTLIAGIMREPFWRFL
LLVTLAKAGRYAVLAMITLGWFHAW