Protein Info for PP_2127 in Pseudomonas putida KT2440

Annotation: Sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 transmembrane" amino acids 31 to 53 (23 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details PF07730: HisKA_3" amino acids 102 to 166 (65 residues), 53.4 bits, see alignment E=4.7e-18 PF13581: HATPase_c_2" amino acids 194 to 265 (72 residues), 30.1 bits, see alignment E=6.7e-11 PF02518: HATPase_c" amino acids 207 to 296 (90 residues), 52.1 bits, see alignment E=1.2e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_2127)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88L10 at UniProt or InterPro

Protein Sequence (313 amino acids)

>PP_2127 Sensor histidine kinase (Pseudomonas putida KT2440)
MCKASISNTSVASLPMFPRLKTSLHCCSRAAVLRWATVGLCVASLIANMALYLANQAIPA
SLLVLQLVATLGAVVQLGLGARSIHLRPAELAERMLKVQEDERQHLGRELHDDIGQLLTA
AKLQLQWLQRRMPDELQGHCDALRSTLDDTLGNVRDVSALLNPRQLASLGLEASLRAHLV
RTLATSGVHWSLACNQRLGGIDEAVAMAVFRITQEAVTNMLRHAQAHNLVIRLQRTPEGL
SLSIQDDGRGFAPARHPAEAGQRGLAGMQERVIALQGSLDITSQPGRGTQIEAMFPWSPR
TQQRARSITNHDL