Protein Info for PP_2102 in Pseudomonas putida KT2440

Annotation: Deoxyguanosinetriphosphate triphosphohydrolase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01353: putative dGTPase
  • amino acids 24 to 435 (412 residues), 322.3 bits, E=3.3e-100
• PF01966: HD
  • amino acids 61 to 124 (64 residues), 27 bits, E=2.3e-10

Best Hits

Swiss-Prot: 87% identical to DGTL2_PSEAB: Deoxyguanosinetriphosphate triphosphohydrolase-like protein (PA14_24730) from Pseudomonas aeruginosa (strain UCBPP-PA14)

KEGG orthology group: K01129, dGTPase [EC: 3.1.5.1] (inferred from 99% identity to ppg:PputGB1_1644)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.5.1

Sequence Analysis Tools

See Q88L33 at UniProt or InterPro

Protein Sequence (443 amino acids)

>PP_2102 Deoxyguanosinetriphosphate triphosphohydrolase-like protein (Pseudomonas putida KT2440)
MDWHTLLTRERLGKALYSADELGRSPFHKDHDRIIFSGAFRRLGRKTQVHPVSSNDHIHT
RLTHSLEVSCVGRSLGMRVGETLRDNLPDWCAPSDLGMIVQSACLAHDIGNPPFGHSGED
AIRHWFQQAAGRGWLDDMSDDERADFLNFEGNAQGFRVLTQLEYHQFDGGTRLTYATLGT
YLKYPWSARHADALGYKKHKFGSYQSELPLLEQIARKLGLPQLEHQRWARHPLVYLMEAA
DDICYALIDLEDGLEMELLQYAEVEALLLDLVGEDLPETYRQLGPRDSRRRKLAILRGKA
IEHLTNAAAHAFVEQQQALLAGQLPGDLVEHMHGPAKRCVLQAKDMARNKIFQDKRKTLH
EIGAYTTLEILLNTFCGAALEQHGGRTPSFKSRRVLDLIGNNAPDPHASLHSAFLRMIDF
IAGMTDSYASEMAREMTGRSSPA