Protein Info for PP_2037 in Pseudomonas putida KT2440

Annotation: putative Aldolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00596: Aldolase_II
  • amino acids 33 to 211 (179 residues), 128.6 bits, E=1.4e-41

Best Hits

KEGG orthology group: K01628, L-fuculose-phosphate aldolase [EC: 4.1.2.17] (inferred from 100% identity to ppf:Pput_3705)

Predicted SEED Role

"Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases"

MetaCyc Pathways

• lactate biosynthesis (archaea) (3/5 steps found)
• D-arabinose degradation II (2/4 steps found)
• L-fucose degradation I (2/4 steps found)
• nucleoside and nucleotide degradation (halobacteria) (2/6 steps found)
• superpathway of fucose and rhamnose degradation (5/12 steps found)
• superpathway of pentose and pentitol degradation (10/42 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.2.17

Sequence Analysis Tools

See Q88L98 at UniProt or InterPro

Protein Sequence (260 amino acids)

>PP_2037 putative Aldolase (Pseudomonas putida KT2440)
MTTTMHTPKDQLVKLAQQQMLTALTDNTYTVRQKLALTCRILFDGGHDSGLAGQITARAQ
EPGTYYTQQLGLGFDEIAASNLLVVDEDLTVLQGHGMANPANRFHSWLYRARPDVNCIIH
THPLHSAALSMLEVPLAISHMDLCPLFDDCAFLKEWPGVPVGNEEGEIIANAIGDKRAIL
LSHHGLLIAGRSIEEACVLALLFERAAKMQLLAMGAGDIRPIPEALGKEAHDWISTPKRH
GAAFSYYARRALRAHGDCLG