Protein Info for PP_2034 in Pseudomonas putida KT2440

Annotation: conserved membrane protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 transmembrane" amino acids 22 to 47 (26 residues), see Phobius details amino acids 50 to 77 (28 residues), see Phobius details amino acids 91 to 126 (36 residues), see Phobius details amino acids 149 to 172 (24 residues), see Phobius details amino acids 178 to 200 (23 residues), see Phobius details amino acids 221 to 240 (20 residues), see Phobius details amino acids 260 to 284 (25 residues), see Phobius details amino acids 292 to 311 (20 residues), see Phobius details amino acids 317 to 334 (18 residues), see Phobius details amino acids 354 to 376 (23 residues), see Phobius details amino acids 382 to 401 (20 residues), see Phobius details PF07690: MFS_1" amino acids 29 to 245 (217 residues), 67.4 bits, see alignment E=5.6e-23 amino acids 251 to 400 (150 residues), 51.2 bits, see alignment E=4.7e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_2034)

Predicted SEED Role

"Fosmidomycin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88LA1 at UniProt or InterPro

Protein Sequence (419 amino acids)

>PP_2034 conserved membrane protein of unknown function (Pseudomonas putida KT2440)
MPCARGARCSTGIDMPHAGPKLLTQIAAVHFVSHVHIMLIPALLPVLPGLLGVGFVELGV
ALAVFNIVSALVQAPLGYAVDHYGARKVLKAGLLLGSLSFVLLAASPGYAVLLVAMAMAG
LANGVYHPADYALLANGIEPARLGRSFSIHTFAGFLGSAVTPAVFLGIAAALGTRAALAA
GAVFGVAALLLISIPGSGVYRVARPANKQDTGPTAATGRVRLFTPMIGVLTVLFILLNLS
TSAIEKFSVAALVQGQGLTLAWANAALTAFLLSSAAGVLCGGALADRTRRHGLVAALAFA
LAAALTALVALGLLQGWALVVVLGAIGLLTGVIAPSRDMLVKAAAPPGAEGKTFGLVSTG
FNVGGAIGPVAFGWMLDQRLPNGIFVASVVFMLLTVLLTLAQEMYSARRRATEQLARAL