Protein Info for PP_1897 in Pseudomonas putida KT2440

Annotation: DNA internalization-related competence protein ComEC/Rec2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 737 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 43 to 59 (17 residues), see Phobius details amino acids 190 to 204 (15 residues), see Phobius details amino acids 222 to 247 (26 residues), see Phobius details amino acids 256 to 274 (19 residues), see Phobius details amino acids 280 to 296 (17 residues), see Phobius details amino acids 303 to 321 (19 residues), see Phobius details amino acids 327 to 347 (21 residues), see Phobius details amino acids 359 to 378 (20 residues), see Phobius details amino acids 387 to 408 (22 residues), see Phobius details amino acids 415 to 434 (20 residues), see Phobius details amino acids 445 to 463 (19 residues), see Phobius details PF13567: DUF4131" amino acids 20 to 167 (148 residues), 86.8 bits, see alignment E=2.1e-28 TIGR00361: DNA internalization-related competence protein ComEC/Rec2" amino acids 109 to 710 (602 residues), 333.6 bits, see alignment E=2e-103 PF03772: Competence" amino acids 198 to 463 (266 residues), 191 bits, see alignment E=4.1e-60 TIGR00360: ComEC/Rec2-related protein" amino acids 219 to 397 (179 residues), 77.7 bits, see alignment E=1.3e-25 PF00753: Lactamase_B" amino acids 497 to 677 (181 residues), 63 bits, see alignment E=5.8e-21

Best Hits

KEGG orthology group: K02238, competence protein ComEC (inferred from 100% identity to ppu:PP_1897)

Predicted SEED Role

"DNA internalization-related competence protein ComEC/Rec2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88LN2 at UniProt or InterPro

Protein Sequence (737 amino acids)

>PP_1897 DNA internalization-related competence protein ComEC/Rec2 (Pseudomonas putida KT2440)
MRTGMFALALGLLCLGFLPALPSVGWLITLAACAVGSLFTRVWPLGWFLLGLCWACGSAQ
QALDDRLATGLEGRTLWLEGRVAGLPARTAHGVRFELEAPRSRRAELPQRLQLSWFDGAP
LRAGEQWRLAVTLQRPNGLLNPHGPDREAQLLARRVGATGTVKAGQLLAPVAGGWRDALR
QRLLMVEANGRQAALVALVLGDGAGLAREDWQTLQATGTVHLLVISGQHIGLVAGLLYGL
VAGLARWGLWPARLPWLPWACGLAMAAALAYGWLAGGGVPVQRACLMLAVVLLWRLRFRH
LGAFFPLLVALVAVLVFEPLAALLPGFWLSFAAVATLIYCFSARLGGWRPWQAWTRAQWV
IAVGLLPVLLATGLPVSLSAPLANLVAVPWVSLAVLPLALLGTLMLPLAGVGEALLWLAG
GLLDVLFRGLALVAQQRPAWVPPALPLWAWLLVCLGVLLVLLPRGVPLRGLGGVMLLALW
VPREPVPFGQVEVWQLDVGQGLAVLLRTRHHSLLYDAGPARGESDLGERVVLPTLRKLGV
GGLDVMVISHAHADHAGGAVAIARGLPIKRIIGGEALVDVPLQPCASGEQWDWDGVRFSL
WRWVDGQSSNDRSCVLLVEAQGERLLLAGDMEAAAERAWLADTEVPRIDWLQAPHHGSRS
SSTEAFVRATAPRGVLISRGRNNSFGHPHVQVVERYGRHGVVMHDTAEEGALRLVLGRHG
VVEGVRGQRRFWRVRGE